The EPSRC Centre for Doctoral Training in Sensor Technologies and Applications, in collaboration with Hitachi, is inviting applications for a fully funded 1+3 years MRes + PhD studentship, commencing in October 2019. The studentship will be hosted in the BioNanoEngineering group (https://www.fruk-lab.com) in the Department of Chemical Engineering and Biotechnology, but will be shared with Department of Radiology, University of Cambridge. The Studentship aims at developing novel radiolabeled nanoparticles for tracking delivery of therapeutic readionuclides and chemotherapeutics to hard-to-treat cancers. This is inspired by recent developments in nanocarrier design, which provided an opportunity to improve the delivery and efficiency of therapeutics for cancer treatment. However, despite the developments, only few nanotechnology inspired formulations made it to the market due to the lack of control over mechanical and physiochemical properties of carriers, limited biological barrier penetration and limited data on their post-drug delivery fate. We want to combine radiolabels, biocompatible nanocarrier and therapeutic cargo to prepare multifunctional nanoparticle system for targeting lung and pancreatic cancer. This work will be performed across the Departments of Chemical Engineering and Biotechnology, Radiology and Oncology, and it will involve use of chemical approaches to nanocarrier design, validation of nanocarriers in in-vivo systems and PET imaging.
For more information, please visit http://www.jobs.cam.ac.uk/job/21545/.