Biography
Clemens Kaminski is Professor of Chemical Physics at the University of Cambridge, UK. He is Director of the EPSRC Centre for Doctoral Training in Sensor Technologies and Applications and Head of the Department of Chemical Engineering and Biotechnology. He obtained his PhD at the University of Oxford, UK, in 1995, held a Marie Curie post-doctoral fellowship and Associate-Professorship at the Lund Institute of Technology in Sweden before his appointment at the University of Cambridge in 2001. He has pioneered the development of advanced imaging techniques for the study of chemical dynamics in technical and biological systems. He is recipient of the Cyril Hinshelwoold prize, Felix Weinberg prize, Philip Leverhulme prize, and the Rosalind Franklin Medal and Prize. Today his group focuses solely on the development and application of of advanced microscopy techniques to unravel molecular mechanisms of disease. Kaminski is a Fellow of Optica, the Royal Society of Chemistry, and the Institute of Physics.
Research
We develop and apply advanced imaging techniques to follow biological processes in living systems with molecular scale resolution. We make use of so called superresolution methods that break the resolution limit imposed by diffraction, molecular biotechnology, and machine learning to study molecular mechanisms of disease. We collaborate widely with medics, biologists, physicists, and engineers to look at the essential processes of living things. We collaborate closely with the Molecular Neuroscience Group, also in this department.
Publications
Scheeder A, Brockhoff M, Ward EN, Kaminski Schierle GS, Mela I, and Kaminski CF. "Molecular Mechanisms of Cationic Fusogenic Liposome Interactions with Bacterial Envelopes" J. Am. Chem. Soc., 145:51 pp 28240–28250 (2023)
Lu M, Christensen CN, Weber JM, Konno T, Läubli NF, Scherer KM, Avezov E, Lio P, Lapkin AA, Kaminski Schierle GS and Kaminski CF. "ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology" Nature Methods 20, 569–579 (2023)
Ward EN, Hecker L, Christensen CN, Lamb JR, Lu M, Mascheroni L, Chung CE, Wang A, Rowlands CJ, Kaminski Schierle GS, Kaminski CF. "Machine learning assisted interferometric structured illumination microscopy for dynamic biological imaging" Nature Commun. 13, 7836 (2022)
Scherer KM, Mascheroni L, Carnell GW, Wunderlich LCS, Makarchuk S, Brockhoff M, Mela I, Fernandez-Villegas A, Barysevich M, Stewart H, Suau Sans M, George CL, Lamb JR, Kaminski-Schierle GS, Heeney JL, Kaminski CF. "SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress" Science Advances. 8:1 (2022)
Lu M, van Tartwijk FW, Lin JQ, Nijenhuis W, Parutto P, Fantham M, Christensen CN, Avezov E, Holt CE, Tunnacliffe A, Holcman D, Kapitein L, Kaminski-Schierle G, Kaminski CF. "The structure and global distribution of the endoplasmic reticulum network are actively regulated by lysosomes" Science Advances 6:51 (2020)
