Prof. Sir David Klenerman
- Royal Society GSK Research Professor
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We are physical scientists interested in developing and applying a range of new quantitative biophysical methods, based on single molecule fluorescence and scanning probe microscopy, to important problems in biology, which have not been addressed to date due to the lack of suitable tools and hence directly image important and disease relevant biological processes at the level of single molecules. While our experiments range from experiments in test-tubes to imaging living cells, no previous biological background is required for our research since we work closely with a range of biological and clinical collaborators. We are also part of the Cambridge Dementia Research centre. The best example of the success of this approach was the development of next generation DNA sequencing see the videos below:
https://www.youtube.com/watch?v=gAbFRUYlkZM