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EPSRC CDT in Sensor Technologies for a Healthy and Sustainable Future

 

Research

Our research is aimed at developing and applying new fluorescence based methods to detect and characterise protein aggregates in biofluids, cells and tissue in order to develop a molecular understanding of what species cause the initiation and spreading of neurodegenerative disease through the brain and the mechanisms by which they damage neurons. We are developing methods to sensitively detect these aggregates in biofluids, such as serum, for early disease diagnosis and monitoring of  the effectiveness of therapies. We are also exploiting these methods to also detect protein aggregates associated with the development of cancer for early cancer diagnosis.

Publications

Other publications: 

A list of publications can be found here.

Professor in Biophysical Chemistry
Professor Sir David  Klenerman